Evidence-based · Updated 2025

Tools for your
metabolic journey.

Evidence-based tools for the GLP-1, peptide, and metabolic medication landscape. Free calculators grounded in STEP, SURMOUNT, and SCALE — plus clinical-trial-backed guides on what's prescribed today and what's coming next.

Based on clinical trial data from STEP, SURMOUNT, and SCALE trials.

STEP-1 · NEJM 2021 SURMOUNT-1 · NEJM 2022 SCALE · NEJM 2015

Calculators

Five tools, all free.

Every calculator runs in your browser. We don't store your inputs.

Weight Loss Projector

See your expected loss curve based on trial data for your medication.

Calorie Target

Find your evidence-based calorie target with a GLP-1-aware deficit.

Protein Needs

Calculate daily protein and how to hit it across smaller GLP-1 meals.

Dose Schedule

Build your full escalation timeline with next-increase date.

Cost Estimator

Estimate monthly out-of-pocket cost by state, insurance, and savings card.

More tools coming: retatrutide projector, peptide reference, compounded medication calculator.

Why GLP1Tree

Built for the long road.

Evidence-based

Projections use published efficacy from peer-reviewed trials, not anecdotes. We cite our sources on every page.

Free forever

No accounts, no paywalls, no email harvesting. Ads keep the lights on so the tools stay free.

Mobile-friendly

Designed for the phone in your pocket on injection day. Share your results with a link.

From the journal

Featured reading.

All articles
Getting Started

What to Expect in Your First 4 Weeks on a GLP-1 Medication

A week-by-week guide to your first month on Ozempic, Wegovy, or Mounjaro — appetite changes, side effects, and what's normal.

10 min read

Getting Started

How Much Weight Will You Lose on a GLP-1? Realistic Expectations from Clinical Trials

Plain-English breakdown of STEP, SURMOUNT, and SCALE trial data — what average weight loss on Wegovy, Mounjaro, and Ozempic looks like in the real world.

10 min read

Next-Gen

The Next Generation of Weight Loss Medications: Retatrutide, Survodutide, and What's Coming After Tirzepatide

Plain-English guide to next-gen weight loss drugs in late-stage trials: retatrutide, survodutide, cagrisema — what they are, how they work, and what the data shows.

11 min read